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Loci


All loci on one chromosome are said to be syntenic (literally on the same ribbon). Loci may appear to be unlinked by conventional genetic tests for linkage but still be syntenic.
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The S loci are (as in SSI plants) extremely polymorphic; that is, there is an abundance of multiple alleles in the population.
Incompatibility is controlled by the single S allele in the haploid pollen grain.
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Locus (loci)
The position on a chromosome where a particular genetic trait resides. Sometimes used to describe multiple genes that affect the same function.
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Disease Loci. Three new disease loci assignments were reported. Kamel Ben Othmane (Duke University) described a recessive form of CMT (Charcot-Marie-Tooth disease) in Tunisians that maps to 8q.
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locus pl. loci
(loh-kus) [L. place]
A particular place along the length of a certain chromosome where a given gene is located.
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A specific loci may contain one of several different coding sequences.
e.g. Many genes have slightly different coding sequences between chromosomes
Macrosatellites also show a similar sequence diversity ...
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Example: 3 loci (polygenic)
Height (tallness) in humans is polygenic but the mechanism of gene function or the number of genes involved is unknown.
Suppose that there are 3 loci with 2 alleles per locus (A, a, B, b, C, c).
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locus (pl. loci)
a particular place along the length of a certain chromosome where a given gene is located.
log (logarithmic) phase
The exponential phase of growth in a bacterial culture.
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Locus (pl. loci): The position on a chromosome of a gene or other chromosome marker; also, the DNA at that position. The use of locus is sometimes restricted to mean regions of DNA that are expressed. See gene expression.
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2. Some genomic loci have been proven very difficult to knock out. Reasons might be the presence of repetitive sequences, extensive DNA_methylation, or heterochromatin.
[edit]
See also ...
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Locus (plural = loci). A specific location or site on a chromosome.
Log phase. See Logarithmic phase.
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Quantitative trait loci (QTL)
The location of a gene that affects a trait that is measured on a quantitative (linear) scale. These traits are typically affected by more than one gene, and also by the environment.
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Distances are established by linkage analysis, which determines the frequency at which two gene loci become separated during chromosomal recombination. (See Mapping.) Genetic marker.
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Homozygote -- having identical alleles at one or more loci in homologous chromosome segments. Housekeeping genes -- those genes expressed in all cells because they provide functions needed for sustenance of all cell types.
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Theology can also be divided up by topic (or by 'loci'):
theology proper - God or the divine: attributes, nature, and relation to the world. Often includes discussion of creation and providence. See the nature of God in Western theology.
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The two alleles of MAT are ideomorphs, meaning that they are unrelated sequences at identical loci.
Cells of either mating type can with low frequency switch to the opposite mating type.
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The word locus (plural loci) is Latin for "place".
In biology and evolutionary computation, a locus is the position of a gene (or other significant sequence) on a chromosome. A locus can be occupied by any of the alleles of the gene.
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At 45 percent of loci in plants there is more than one allele in the gene pool. [allele: alternate version of a gene (created by mutation)] Any given plant is likely to be heterozygous at about 15 percent of its loci.
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One case of this phenomenon occurs at loci at the major histocompatibility complex (MHC) wherein some human alleles are much more closely related to some chimpanzee alleles than they are to other human alleles (Fig. 7).
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Distance between two loci. Recombination can be used to determine map distance between two loci. A map distance of 1 centiMogan (cM) is equivalent to the recombination rate of 1%.
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This usually occurs at loci such as immunoglobulin or T cell receptor (
TCR
) genes where a functional rearrangement among genes takes place. One of the alleles is
either non-functionally or incompletely rearranged and
not expressed.
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A statistical estimate of whether two loci are likely to lie near each other on a chromosome and are therefore likely to be inherited together. A LOD score of three or more is generally taken to indicate that the two loci are close.
explained: ...
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a measure of distance between two gene loci based on the frequency of crossing over between them; one map unit is equivalent to one percent crossing over
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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quantitative trait A genetic trait that is determined by multiple interacting loci, and for which there is a range of phenotypes between phenotypic extremes.
quark A subatomic particle found in the nucleus of the atom.
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Human beta-globin genes are scattered at five loci on human chromosome 11. These genes are expressed sequentially during development, and are similar with same-length introns in similar positions in each gene.
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