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Linker


Linker
A short synthetic double-stranded DNA. Usually ligated to double-stranded DNA to introduce restriction sites or sequence tags (e.g., for PCR).
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Linker
A synthetic, double-stranded oligonucleotide used to attach sticky ends to a blunt-ended molecule.
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LINKER - A short oligodeoxyribonucleotide, usually representing a specific restriction endonuclease recognition sequence, which may be ligated onto the termini of a DNA molecule to facilitate cloning.
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Linker: A small piece of synthetic double-stranded DNA which contains something useful, such as a restriction site. A linker might be ligated onto the end of another piece of DNA to provide a desired restriction site.
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Linker. A short, double-stranded oligonucleotide containing a restriction endonuclease recognition site, which is ligated to the ends of a DNA fragment. Liposomes.
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Since we developed the chromosome microdissection and MboI-linker adaptor microcloning techniques, ...
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The current understanding[9] is that repeating nucleosomes with intervening "linker" DNA form a 10-nm-fiber, known descriptively as "beads on a string", and have a packing ratio of ~6, compared to "free" DNA (per nm length).
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Repeating nucleosomes with intervening "linker" DNA form the 10-nm-fiber, known descriptively as "beads on a string", and have a packing ratio of ~6, compared to "free" DNA (per nm length).
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Serious damage, e.g., double-stranded breaks (DSBs), causes a linker histone (H1) to be released from the chromatin.
H1 leaves the nucleus and enters the cytosol where
it triggers the release of cytochrome c from mitochondria leading to
apoptosis.
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The core consists of two molecules each of H2A, H2B, H3, and H4; around which the DNA is wound twice. The H1 histone is outside the core. Between 150-200 nucleotide pairs are associated with the core and linker DNA.
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polylinker A short, usually synthetic, fragment of DNA containing recognition sequences for several restriction endonucleases employed to insert DNA into plasmids.
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