Linkage

linkage
inheritance of traits in groups because their genes are near each other (linked) on the same chromosome
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby ...
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A group of gene loci known to be linked; a chromosome. There are as many linkage groups as there are homologous pairs of chromosomes. See synteny.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Linkage
An association in inheritance between characters such that the parental character combinations appear among the progeny more often than the non-parental.
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Genetic Linkage and Genetic Maps
The Background
Gregor Mendel analyzed the pattern of inheritance of seven pairs of contrasting traits in the domestic pea plant.
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Dr. Leslie Biesecker, of the National Human Genome Research Institute's Laboratory of Genetic Disease Research, defines linkage.
related
terms:
base pair, chromosome, deoxyribonucleic acid (DNA), gene, genetic marker, inherited ...
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Genetic linkage occurs when two alleles are in close proximity to each other. During the formation of the gametes, recombination of the genetic material results in reshuffling of the alleles.
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Linkage and physical mapping goals engendered the most discussion. With respect to linkage maps of each human chromosome, advisors agreed that for the next 5-year period, ...
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Linkage of genetic markers during conjugal transfer in bacteria can be used to construct genetic maps.
Facts ...
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Linkage
The tendency of genes located close together on the same DNA molecule to be coinherited. Typically expressed as percent coinheritance of two genetic markers.
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Linkage disequilibrium is a measure of association between alleles of two different genes.
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linkage The condition in which the inheritance of a specific chromosome is coupled with that of a given gene. The genes stay together during meiosis and end up in the same gamete.
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linkage map
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes. The greater the frequency of recombination between two genetic markers, the farther apart they are assumed to be.
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Linkage
In peas, the locus for seed texture (smooth or wrinkled) and seed color (yellow or green) are on two different chromosomes so they assort independently.
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linkage group Genes linked to the same chromosome that tend to be inherited together.
linkage Tendency of genes located on the same chromosome to be inherited together.
linked gene Gene located on the same chromosome as another gene.
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Linkage. The frequency of coinheritance of a pair of genes and/or genetic markers, which provides a measure of their physical proximity to one another on a chromosome.
Linkage map. See Genetic linkage map.
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LINKAGE - The tendency of genes to be inherited together as a result of their relatively close proximity on the same chromosome, or location on the same plasmid.
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Linkage: The measure of proximity of two or more markers (e.g., genes, RFLP markers) on a chromosome determined by recombination events.
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Sex linkage
Where the a gene is sex-linked, the heterogametic sex (e.g. males in humans) have only one copy of the gene and are effectively haploid for that gene.
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gene linkage: the concept of transfer of a linkage group.
gene linkage map: a map that pinpoints the location of genes based on their connection to certain marker gene sequences.
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: see
linkage disequilibrium
.
Allelic exclusion
: Expression of only one of the two homologous alleles at a locus in the case of heterozygosity.
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phosphodiester linkage - covalent bond that joins the 5' and 3' carbon atoms to form
nucleic acids
peroxisomes - small membrane -bounded organelle that uses molecular oxygen to oxidize organic molecules.
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Gene linkage. The hereditary association of genes located on the same chromosome. Gene modification. The chemical repair of a gene's defective DNA sequence. See DNA. Gene pool.
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Deletion mapping -- the use of overlapping deletions to localize the position of an unknown gene on a chromosome or linkage map.
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peptide bond A planar, amide linkage between the a-amino group of one amino acid and the a-carboxyl group of another, with the elimination of a molecule of water.
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5' or 3' end The nucleoside residues which form nucleic acids are joined by phosphodiester linkages between the 3' C atom of one ribose moiety and the 5' C atom of the next.
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Now it was largely lost, to be replaced by the rule of local potentates, and the gradual break-down of economic and social linkages and infrastructure.
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Once we had done this we used linkage, which is a family-based method, to look at segments of DNA that are yet to be affected in members of the family. We established linkage to Chromosome 8.
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You might be looking for linkage between a microsatellite marker and an unknown disease gene. With such information, you can infer the chromosomal location of the unknown gene, and can sometimes identify the gene.
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Lactase an enzyme used to digest the -1-4 glycosidic linkage in milk sugar
(lacto = milk; -ase = enzyme ending) ...
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A set of closely linked genetic markers present on one chromosome which tend to be inherited together (not easily separable by recombination). Some haplotypes may be in linkage disequilibrium.
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because users' definition of "distance" is related to "similarities" or "correlation". There are a large number of variants of hierarchical clustering. The differences are in the way distances are defined and computations (e.g., average-linkage, ...
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The downside of the mobile mechanism of the serpins is their vulnerability to aberrant intermolecular b-linkages, resulting in various disorders from cirrhosis to thrombosis.
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