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Kinetochore


Kinetochore
Structure forming at centromere during mitosis for binding microtubules.
Related Terms: Centromere ...
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kinetochores Structures at the centromeres of the chromosomes to which the ?bers of the mitotic spindle connect. PICTURE ...
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kinetochore A disc of proteins located on the centromere, specialized to interact with the spindle fibers during mitosis.
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kinetochore
(kih-net-oh-kor) [Gk. kinetikos, putting in motion + choros, chorus]
A specialized region on the centromere that links each sister chromatid to the mitotic spindle.
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Kinetochores and Kinetochore Microtubules
During prophase, protein plates called kinetochores form on the centromeres of each chromosome.
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kinetochore: a region of DNA that has remained undivided during prophase of mitosis; binds to the spindle fibers that eventually pull apart the sister chromatids.
kingdom: the largest and broadest category of the classification system.
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Kinetochore microtubules shorten, severing the recombination nodules and pulling homologous chromosomes apart. Since each chromosome only has one kinetochore, whole chromosomes are pulled toward opposing poles, forming two haploid sets.
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kinetochore - structure that attaches a eukaryotic chromosome to the spindle apparatus for separation during mitosis; adjacent to the centromere.
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A kinetochore; the constricted region of a nuclear chromosome, to which the spindle fibres attach during division.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Now kinetochores begin to form at the centromeres. This is a complex protein structure that may be thought of as an 'eyelet' for the microtubule 'rope' - it is the attaching point by which chromosomes may be secured.
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sister kinetochores of one homologue, pulling both sister chromatids toward one pole of the cell;
sister kinetochores of the other homologue pulling those sisters toward the opposite pole.
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Attachment of chromosomes at centromeres to kinetochores is essential for segregation.
In meiosis I, sister chromatids must remain attached to one another. A protein factor may be required to prevent their premature dissociation.
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the structure located at a specific site on the chromosome that holds the two chromatids together; it is the site of attachment for the spindle fibers during cell division; also called primary constriction or kinetochore ...
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The centromere is generally flanked by repetitive DNA sequences and it is late to replicate. The centromere is an A-T region of about 130 bp. It binds several proteins with high affinity to form the
kinetochore ...
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