Histone

histone
a type of basic protein associated with DNA in chromosomes
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Histone modifications in chromatin regulation
Histones undergo posttranslational modifications which alter their interaction with DNA and nuclear proteins.
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Definition of histone : ...
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These enzymes add an acetyl group to histones, thus releasing the restricted access to DNA imposed by histones. Transcription factors can then bind to the DNA, allowing gene transcription to occur.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Histone
In biology, histones are the chief proteins of chromatin. They act as spools around which DNA winds and they play a role in gene regulation. Histones are found in the nuclei of eukaryotic cells.
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Histone
Protein associated with DNA in chromosomes in the nucleus of the cell.
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Histone Modifications
Although their amino acid sequence (primary structure) is unvarying, individual histone molecules do vary in structure as a result of chemical modifications that occur later to individual amino acids.
These include adding: ...
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Histone
A basic protein from eukaryotes (or Archae) which binds to DNA, forming nucleosomes, and packaging the DNA into chromatin.
Histone-like proteins
Proteins from bacteria which bind to DNA, and compact the DNA.
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histone proteins Proteins associated with DNA in eukaryote chromosomes.
homeobox genes Pattern genes that establish the body plan and position of organs in response to gradients of regulatory molecules.
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histones -- proteins attached to the DNA of eukaryotes which allows it to be packaged into chromosomes.
hydrophilic -- "water loving". Hydrophilic compounds dissolve easily in water, and are usually polar.
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histone
(hiss-tone)
A small protein with a high proportion of positively charged amino acids that binds to the negatively charged DNA and plays a key role in its chromatin structure.
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histones: nuclear proteins that coil DNA molecules.
homeostasis: the process in which the internal environment exists at a steady-state equilibrium despite changes in the external environment.
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histone Any of several simple proteins found in cell nuclei and complexed at one time or another with DNA. Histones yield a high proportion of basic amino acids on hydrolysis; characteristic of eukaryotes.
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histones - basic proteins that bind and "package" eukaryotic DNA; major protein constituent of chromosomes.
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Histones: Highly basic proteins which associate with the chromosomal DNA to package it into a compact, higher order structure.
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A single DNA molecule, a tightly coiled strant of DNA, condensed into a compact structure in vivo by complexing with accessory histones or histone-like proteins. Chromosomes exist in pairs in higher eukaryotes.
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A nucleosome consists of a DNA strand wound around an octameric histone core. nucleotide A nucleoside phosphorylated at one of its pentose hydroxyl groups.
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melanogaster histone gene unit is moderately repetitive DNA, is arranged in tandem repeats, and has products that are required in large amounts by all cells.
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In 19951996 we continued to map and identify nonhistone proteins binding at loci along the yeast chromosome.
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: The complex of DNA and associated histone and non-histone proteins that represents the normal state of genes in the nucleus.
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When DNA condenses, the molecule becomes wrapped around proteins called histones. The histones are then arranged in a coiled pattern to produce a larger fiber. This larger fiber is further compacted by looping to produce looped domains.
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Chromosome organized in nucleosomes composed of histones and other protein factors.
Related
Chromosome ...
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the DNA strand may also be silenced through DNA methylation or by chemical changes to the protein components of chromosomes (see histone). This is a permanent form of regulation of the transcription.
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It is thought that the presence of this "polyA tail" increases the stability of the mRNA (possibly by protecting it from nucleases). Note that not all mRNAs have a polyA tail; the histone mRNAs in particular do not.
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141-154 15 Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes Dominique Helmlinger, Sara Hardy, Adrien Eberlin, Didier Devys and Làszlò Tora..........
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