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Heterozygous


heterozygous
pertaining to two different alleles at a specific locus in a diploid organism
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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For example, the gene for seed shape in pea plants exists in two forms, one form or allele for round seed shape (R) and the other for wrinkled seed shape (r). A heterozygous plant would contain the following alleles for seed shape: (Rr).
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Dr. Robert Nussbaum, of the National Human Genome Research Institute's Laboratory of Genetic Disease Research, defines heterozygous.
related
terms:
chromosome, gene, inherited ...
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heterozygous Having two different alleles (one dominant, one recessive) of a gene pair.
histamine A chemical released during the inþammatory response that increases capillary blood þow in the affected area, causing heat and redness.
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heterozygous: two different alleles that are present for a particular characteristic.
hindbrain: the portion of the brain that consists of the medulla, pons, and cerebellum.
histones: nuclear proteins that coil DNA molecules.
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heterozygous A genotype for a given phenotypic expression containing a dominant and a recessive allele for that trait.
hexacanth Oncosphere; a six-hooked larva hatching from the egg of a eucestode.
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Heterozygous recessive traits
In some instances, efforts to eradicate certain single-gene mutations would be nearly impossible.
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Heterozygous: An individual containing dissimilar alleles for a given gene or locus.
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A heterozygous carrier of red-green colorblindness has some colorblind cells in her retina. The non-colorblind cells enable her to see color.
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: A (heterozygous) dominant mutation on one allele blocking the activity of wild-type protein still encoded by the normal allele (often by
dimerising
with it) causing a loss-of-function phenotype.
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Mate two heterozygous mice and screen their offspring for the 1:4 that will be homozygous for the transgene.
Mating these will found the transgenic strain.
The Pronucleus Method (Method "2")
1. Prepare your DNA as in Method 1 ...
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An organism heterozygous at three loci.
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A Method for Heterozygous Carrier Screening Using an E. coli Mismatch Binding Protein, MutS; Application to the Cystic Fibrosis Gene ...
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Carrier -- an individual heterozygous for a single recessive gene. cDNA -- complementary DNA produced from a RNA template by the action of RNA- dependent DNA polymerase.
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A condition where a heterozygous off- spring has a phenotype that is distinctly different from, and intermediate to, the parental phenotypes. See Heterozygote, Phenotype. Initiation codon.
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ci-/- embryos derived from ci94 mutant germline clones (Fig 6I) are indistinguishable from ci-/- embryos derived from heterozygous mothers (Fig 6H) (Methot, 2001) ...
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If sickle cell anemia is so deadly, why are so many people heterozygous carriers of the disease? Moreover, why does the disease afflict predominantly one racial group? Surpisingly, the answer has to do with malaria.
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Individual immunoglobulin producing cells of heterozygous individuals produce immunoglobulins of a single allotype. The phenomenon is called allelic exclusion.
Immunoglobulin synthesizing cells have one or both heavy chain gene loci rearranged.
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Heterozygosity is simply the proportion of the population that is heterozygous. Equilibrium heterozygosity is given as H = 4Nv/[4Nv+1] (for diploid populations). H can vary from a very small number to almost one.
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An organism which has two different alleles of the gene is said to be heterozygous. Often one allele is "dominant" and the other is "recessive" - the "dominant" allele will determine what trait is expressed.
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When a single trait is being studied, a test cross is a cross between an individual with the dominant phenotype but of unknown genotype (homozygous or heterozygous) with a homozygous recessive individual.
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Recessive
A genetic trait that is not expressed in a heterozygous or partially heterozygous cell.
Recombinant DNA
A molecule of DNA in which a DNA fragment from a different source has been inserted.
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A hybrid individual that is heterozygous for two genes or two characters.
dihybrid cross
A breeding experiment in which parental varieties differing in two traits are mated.
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