Chapter 9
Use of anti-neo
epitope antibodies for the ana
lysis of degradative events in
cartilage and the molecular basis for neo
epitope specificity
John S.Mort*1, Carl R. Flannery2, Joe Makkerh*3, Joanne C. Krupa* and Eunice R. Lee* ...
Full article >>>EpitopeA portion of an
antigen recognized by an
antibody binding site. For
protein antigens the
epitope is typically 5-8
amino acids.
Gene fusions to
epitopes can be used as a tag to recognize specific
proteins.
Full article >>>epitopeA
localized region on the surface of an
antigen that is chemically recognized by
antibodies; also called
antigenic determinant.
equilibrium ...
Full article >>>epitope Antigenic determinant; the portion of the
antigen molecule displayed on the surface of an
antigen-presenting
cell (APC).
epizootic Massive infection rate among
animals other than
humans; identical to an epidemic in
humans.
Full article >>>Epitope: As related to
protein antigens, B-
cell epitopes consist of the
amino acid residues of a
protein molecule which interact directly through noncovalent bonds with the
amino acid residues of a particular
antibody molecule (
complementarity ...
Full article >>>Epitope: The specific
site on an
antigen that is recognized by an
antibody (also known as the
antigenic determinant).
Escherichia coli ...
Full article >>>Most
epitopes are derived from
polypeptides (
proteins) and reflect the individuality of the
pathogen.
Receptors are PRRs (pattern recognition
receptors)
In jawed
vertebrates, the
receptors are B-
cell (BCR) and T-
cell (TCR)
receptors for
antigen ...
Full article >>>Two very similar
epitopes, Cc and Ee, appear to be closely related to Rh.
Rare
phenotypes
Bombay
phenotype ...
Full article >>>Immunoglobulin
molecules of single-
epitope specificity that are secreted by a
clone of B
cells.
Monoculture. The agricultural practice of cultivating crops consisting of genetically similar
organisms.
Monogenic.
Full article >>>ePitope Informatics epitope prediction and ana
lysis;
protein epitopes
European Directory of
DNA Laboratories (ED
DNAL) intended mainly for clinical geneticists and molecular
biologists.
Full article >>>Each B-
lymphocyte produces
antibodies that are specific not to an
antigen, but to an
epitope of that
antigen. An
epitope is a small piece of the
antigen to which the
antibody binds.
Full article >>>Monoclonal antibodies. Immunoglobulin
molecules of single-
epitope specificity that are secreted by a
clone of B
cells.
Monoculture. The agricultural practice of cultivating crops consisting of genetically similar
organisms.
Full article >>>A mixture of immunoglobulin
molecules secreted against a specific
antigen, each recognizing a different
epitope.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
Full article >>>Different
antibodies in the pool recognize different
epitopes of the
antigen. poly
linker A short, usually synthetic, fragment of
DNA containing recognition
sequences for several
restriction endonucleases employed to
insert DNA into
plasmids.
Full article >>>So some of these
amino acids would be located on the surface of the
protein, directly accessible to the
environment. Those
amino acid residues would be the most that would constitute usually
antigenic
epitopes.
Full article >>>'"/>