Downstream

Upstream/Downstream
Refers to 5' or 3' to a reference point in RNA. In double-stranded DNA, upstream/downstream is relative to a transcription unit: up to down is the direction of transcription.
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Downstream
The region extending in the 3' direction from a gene.
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Downstream
A sequence located after a particular site relative to the direction of transcription and translation (i.e. located to the 3' side of a particular site). For example, the lacZ structural gene is located downstream of the lac promoter.
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Downstream from TNF-R1 and Fas activation - at least in mammalian cells - a balance between pro- (like BAX, BID, or BAD) and anti-apoptotic (Bcl-Xl and Bcl-2) members of the Bcl-2 family is compromised.
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DOWNSTREAM - Identifies sequences proceeding farther in the direction of expression; for example, the coding region is downstream from the initiation codon, toward the 3' end of an mRNA molecule.
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Downstream. The region extending in a 3' direction from a gene.
dscDNA. See double-stranded complementary DNA.
Duplex DNA. Double-stranded DNA.
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Downstream: See "Upstream/Downstream".
E. coli: A common Gram-negative bacterium useful for cloning experiments. Present in human intestinal tract. Hundreds of strains of E. coli exist. One strain, K-12, has been completely sequenced.
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Downstream: See "Upstream/Downstream".
Duplex: A nucleic acid molecule in which two strands are base paired with each other.
E ...
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Downstream
: The direction which RNA polymerase moves during transcription (5' to 3') and ribosomes moves during translation.
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Smo acts downstream of hh and ptc (Alcedo, 1996)
Hh mut & PKA mut had ptc RNA; Smo mut & PKA mut had no ptc RNA -> suggest that smo has a significant basal activity in the absence of Hh (Ohlmeyer, 1997) ...
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New types of "downstream" public databases are also being developed for information such as gene expression patterns. Although the idea of a single, integrated database sounds appealing, this is probably not feasible.
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Downstream. The region extending in a 3' direction from a gene. dscDNA. See double-stranded complementary DNA. Duplex DNA. Double-stranded DNA. E Ecology. The study of the interactions of organisms with their environment and with each other.
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Recall that transcription termination often occurs at sites considerably downstream of the sites that, after polyadenylation, are the 3' ends of most eukaryotic mRNAs.
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And that's a great question and because we really don't know what SRY is doing downstream we can't answer that question yet. Everybody wants to say it activates another gene, but it could easily repress a gene.
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Water that id dammed up no longer freely flows, placing wetland habitats downstream from the dam at risk.
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It is thought that this constitutes the mechanism of choice, and allows downstream processes to establish the compact state of the Barr body.
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Enhancers differ from promoters in being farther away from, and either upstream (5') or downstream (3') of, the gene they influence.
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It is known for the downstream executioner caspases-3 and -7 that the activation event is proteolytic cleavage, and this had been assumed to apply to the initiator caspases as well.
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oxygen sag Oxygen decline downstream from a pollution source that introduces materials with high biological oxygen demands.
oxyhemoglobin Compound formed when oxygen combines with hemoglobin.
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During the early 1850's the Sacramento valley was devastated by floods, fires and from cholera epidemics. Despite this, because of its position just downstream from the Mother Lode in the Sierra Nevada, the newfound city grew, ...
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If a transposon inserts itself within another gene, it can prevent the gene from expressing itself. Sometimes the transposon carries a gene which can become activated if it becomes inserted downstream from an active promoter.
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