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Double helix


Double helix stairway in the Vatican Museum
Image of a DNA chain - showing the double helix ...
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From Double Helix to Human Sequence - and Beyond!
Natcher Auditorium, Rockville, MD April 14th and 15th, 2003
A two day scientific symposium where more than 35 participants will discuss the science and history of the Human Genome Project.
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The double helix of DNA has these features:
It contains two polynucleotide strands wound around each other.
The backbone of each consists of alternating deoxyribose and phosphate groups.
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Double helix
The term Double helix (plural helices) describes the structure of DNA as first published by James Watson and Francis Crick in 1953.
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Dr. Francis Collins, director of the National Human Genome Research Institute, defines double helix.
related
terms:
base pair, deoxyribonucleic acid (DNA), nucleotide ...
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Double helix
The shape that two linear strands of DNA assume when bonded together.
Messenger RNA (mRNA) ...
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double helix
The form of native DNA, referring to its two adjacent polynucleotide strands wound into a spiral shape.
Down syndrome ...
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double helix A helix composed of two molecules winding around each other, as in DNA.
dourine Disease of horses and other equids caused by Trypanosoma equiperdum.
down feathers Feathers that provide insulation for adult and immature birds.
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Double helix: The helical shape assumed by DNA in which the two complementary strands hydrogen bond together in opposite orientations (i.e. have opposite polarities).
Downstream: See "Upstream/Downstream".
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A DNA double helix formed by annealing single strands from different sources; if there is a sequence difference between the strands, the heteroduplex may show single strand loops or bubbles (unpaired regions).
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DNA is a double helix, with bases to the center (like rungs on a ladder) and sugar-phosphate units along the sides of the helix (like the sides of a twisted ladder).
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Double helix. Describes the coiling of the antiparallel strands of the DNA molecule, resembling a spiral staircase in which the paired bases form the steps and the sugar-phosphate backbones form the rails. Double-stranded complementary DNA (dscDNA).
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base pair a pair of hydrogen-bonded nitrogenous bases (one purine and one pyrimidine) that join the component strands of the DNA double helix.
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Watson, The Double Helix: A Personal Account of the Discovery of the Structure of DNA, Atheneum, 1980, ISBN 0689706022 (first published in 1968) is a very readable first hand account of the research by Crick and Watson.
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These bonds, which bind the complementary strands of DNA together in a double helix, are broken at elevated temperatures (about 95 C). Each single-stranded piece of DNA (ssDNA) is then built upon to form a new, double-stranded molecule (dsDNA).
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Proteins that unwind the DNA double helix.
Hemimethylation
Double stranded DNA in which only one strand is methylated at a particular site. For example, at GATC sites in E.
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DNA is composed of two anti-parallel strands which wind about a common axis to form a double helix.
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The model showed that DNA is a double helix with sugar-phosphate backbones on the outside and the paired nucleotide bases on the inside, in a structure that fit the spacing estimates from the X-ray diffraction data.
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DNA: deoxyribonucleic acid; a double helix nucleotide molecule containing deoxyribose, nitrogenous base, and a phosphate group; contains the genetic information from which amino acids are determined.
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DNA helicase - an enzyme that participates in DNA replication by unwinding the double helix near the replication fork
DNA ligase - fills in nicks and gaps made in polynucleotide strands ...
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Domi nant gene: A gene which, when present on a chromosome, passes on a certain physical characteristic, thereby dominating over a recessive gene present on another chromosome. Double helix: A common name for DNA; ...
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The major component of the thin filaments is F-actin, a filamentous protein composed of helical polymeric chains of the globular protein, G-actin. The double helix of the actin filament has 13 G-actin molecules (diameter about 5.6 nm) per turn.
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The recA protein binds single-stranded DNA, incorporating the DNA into a helical complex with 6 recA molecules and 22 nucleotides/ turn. Adjacent bases are 1.5 times as far apart as they are in a B-DNA double helix.
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double helix The natural coiled conformation of two complementary, antiparallel DNA chains by the formation of A-T and G-C base pairs.
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