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Complementation


The production of a wild-type phenotype when two different mutations are combined in a diploid or a heterokaryon. The production of the wild-type phenotype by a cell or an organism that contains two mutant genes. If complementation occurs the ...
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Complementation test
A mating test to determine whether two different recessive mutations (a1;a2) on opposite chromosomes (trans, a1+/+a2) of a diploid or partial diploid will not complement (ie have a mutant phenotype) each other; ...
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Complementation
As we saw above, rapid lysis (r) mutants were found that mapped to three different regions of the T4 genome: rI, rII, and rIII.
This meant that ...
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Complementation
The ability of a gene to produce a functional gene product which compensates for the mutant phenotype caused by a mutation in another gene. Typically, the complementing gene produces a gene product (e.g.
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Complementation
: The production of a wildtype phenotype when two recessive mutations from different genes are brought together.
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(1) In vivo complementation for cloning mouse mutations. We developed an in vivo library of the 550 kb region to which the mouse recessive neurological mutation vibrator had been localized by meiotic mapping.
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One set of such mutations falls into four complementation groups, uvrA through uvrD.
Biochemical studies of the proteins encoded by the genes, coupled with genetic studies, revealed a role in DNA repair.
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