Navigation Links
Albumin


You may be looking for albumen, or egg white.

Albumin is a blood plasma protein that is produced in the liver and forms a large proportion of all plasma protein. It is also found in egg white.

The normal range of albumin concentrations in human blood is 3.5 to 5.0 g/dL, and albumin normally constitutes about 60% of plasma protein; all other proteins present in blood plasma are referred to collectively as globulin. Albumin is essential for maintaining the oncotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. Albumin is negatively charged. The glomerular basement membrane is also negatively charged, this prevents the filtration of albumin in the urine. In nephrotic syndrome, this property is lost, and there is more albumin loss in the urine.

Because smaller animals (for example rats) function at a lower blood pressure, they need less oncotic pressure to balance this, and thus need less albumin to maintain proper fluid distribution.

Functions of albumin:

  • Maintains oncotic pressure
  • Transports thyroid hormones
  • Transports other hormones, particularly fat soluble ones
  • Transports fatty acids ("free" fatty acids)
  • Transports unconjugated bilirubin
  • Transports many drugs
  • Competitively binds calcium ions (Ca2+)
  • Buffers pH

Causes of albumin deficiency:

  • Cirrhosis of the liver (most commonly)
  • Decreased production (as in starvation)
  • Excess excretion by the kidneys (as in nephrotic syndrome)
  • Excess loss in bowel (protein losing enteropathy)
  • Mutation causing albuminemia (very rare)

Links


'"/>


(Date:7/21/2014)... streamlined and simplified a process that uses extracts from ... levels of harmful bacteria by 90% to 99%. The ... throughout many countries of Africa, Asia, and Latin America. ... Current Protocols in Microbiology review, is low-cost and ... extreme poverty in developing countries who are presently drinking ...
(Date:7/21/2014)... climate change, due to greenhouse gasses emitted by livestock. ... rise and that beef cattle are responsible for far ... It is published by Climactic Change . ... comes to climate change. It is released by vehicles, ... of greenhouse gas totals. But methane and nitrous oxide ...
(Date:7/21/2014)... of high-fat foods cause you to lose your sense ... University neuroscientists says so, and it has researchers taking ... a whole range of human functions that were not ... "This opens up a lot of possibilities for obesity ... who led the study examining how high-fat foods impacted ...
Breaking Biology News(10 mins):Climate: Meat turns up the heat 2New research links bad diet to loss of smell 2
... Science Research Conference on focuses on recent advances in ... transcriptional regulators, currently numbering 17, and will also include ... Held twice previously, this FASEB Conference is the ... The major themes of the conference will be the ...
... medicine? The media are invited to register now for ... Clinical Genetics Meeting, March 25-29, 2014 at the Nashville ... Sequencing to Cancer Genetics, the focus of the ACMG ... genomics in healthcare, showcasing the latest breakthroughs in genetics ...
... European consortium of epilepsy researchers has reported the discovery ... Using a novel combination of technologies, including trio exome ... tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found ... a subset of epilepsy patients with symptoms similar to ...
Cached Biology News:Complimentary press registration now open for ACMG 2014 Annual Clinical Genetics Meeting 2European epilepsy consortium identifies new gene for severe childhood epilepsy 2European epilepsy consortium identifies new gene for severe childhood epilepsy 3European epilepsy consortium identifies new gene for severe childhood epilepsy 4
Other biology definitionOther Tags